What medicine can be used for premature ejaculation?
Premature Ejaculation (PE) is one of the common sexual dysfunctions in men and has become a hot health topic on the Internet in recent years. Many patients hope to improve their symptoms with medication. This article will combine the popular discussions and medical data on the Internet in the past 10 days to sort out the commonly used drugs and precautions for premature ejaculation.
1. Common drug treatments for premature ejaculation

| drug type | Representative medicine | Mechanism of action | Things to note |
|---|---|---|---|
| SSRI antidepressants | Dapoxetine, Paroxetine | Regulates serotonin levels, delays ejaculation | It needs to be taken as needed or regularly. Dizziness may be a side effect. |
| local anesthetic | lidocaine gel | Reduce glans sensitivity | Need to be used 20 minutes before sexual intercourse to avoid numbness of partner |
| PDE5 inhibitors | Sildenafil (Viagra) | Improve erectile function and indirectly extend sexual intercourse time | Doctor's guidance is required and should not be used together with nitrates. |
| Chinese medicine preparations | Cynomorium Gujing Pills, Jingui Shenqi Pills | Tonify the kidneys and strengthen essence, regulate the body’s constitution | It requires syndrome differentiation and treatment, and the course of treatment is relatively long. |
2. Recent hot topics on the Internet
1.Dapoxetine OTC Trends: Many countries are discussing the possibility of turning the drug into an over-the-counter drug, sparking controversy over the safety of self-medication.
2.Review of New Delay Spray: Experience sharing of "plant ingredient" delayed products has appeared on multiple social platforms, but there is a lack of clinical verification.
3.combination treatment plan: Medical forums are hotly discussing the comprehensive intervention model of "drugs + behavioral therapy", and data show that the effective rate has increased to 82%.
| treatment plan | efficient | recurrence rate |
|---|---|---|
| Medication alone | 58-65% | 35-42% |
| Medication + behavioral therapy | 78-82% | 18-22% |
| simple behavioral training | 45-50% | 50-55% |
3. Medication precautions
1.individual differences principle: The effect of the same drug on different patients can vary by up to 40%, and the dosage needs to be adjusted under the guidance of a doctor.
2.side effect management: SSRI drugs may cause nausea (the incidence is about 15%), headache (12%), etc., which usually resolve within 2 weeks.
3.drug interactions: Dapoxetine should be used with caution in combination with antifungal drugs and HIV protease inhibitors as it may increase the risk of adverse reactions.
4. Non-drug auxiliary measures
| method type | Specific measures | efficient |
|---|---|---|
| behavioral training | Stop-and-go method, squeeze method | 60-70% |
| psychological intervention | cognitive behavioral therapy | 55-65% |
| lifestyle | Pelvic floor muscle exercise, smoking cessation and limiting alcohol consumption | 40-50% |
5. Medical advice
1. When symptoms appear for the first time, it is recommended to see an andrology department or urology department to rule out organic diseases such as prostatitis.
2. If the effect is not good after 4 weeks of medication, you should consider adjusting the treatment plan.
3. Recent online consultation data show that about 37% of premature ejaculation patients are accompanied by mild depressive symptoms and require multidisciplinary collaborative treatment.
Note: The data in this article are based on public discussions in PubMed, CNKI and major health platforms in the past 10 days. Please follow your doctor's advice for actual medication use. Some new treatments require more clinical verification, and consumers should be wary of products with exaggerated claims.
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